A Transdermal Patch is an adhesive patch that has a coating of medicine (drug) that is placed on the skin to deliver specific dose of the medicine (drug) into the bloodstream over a period of time. The skin can be used as the site for drug administration for continuous transdermal drug infusion into the systemic circulation. For the continuous diffusion/penetration of the drugs through the intact skin surface membrane-moderated systems, matrix dispersion type systems, adhesive diffusion controlled systems and micro reservoir systems have been developed. Various penetration enhancers are used for the drug diffusion through skin. This review article provide a valuable information of the principles of trasdermal permeation, various components of transdermal patch, approaches of transdermal patch, evaluation of transdermal system.
Loading....